OMG...years ago when i was in the midst of a breakdown my doc trying earnestly to ger me some help gave me zoloft....I remember the last thing I needed was any more problems at that particular time....but the medication gave me the runs, i couldnt sleep, I felt like I was on speed...like i was living on rails.....and I swear that easily couldve been the end of me had I had a strong urge to suicide.....somehow I got through it and effexor saved my life.....getting off it is another matter that most are aware of.